Conveners
Biomedicine & Life Science Session
- Danny HSU (Academia Sinica)
Dr
Alexandre M.J.J. Bonvin
(Utrecht University)
20/03/2018, 14:00
Biomedicine & Life Sciences Applications
Oral Presentation
Structural biology deals with the characterization of the structural (atomic coordinates) and dynamic (fluctuation of atomic coordinates over time) properties of biological macromolecules and adducts thereof. Since 2010, the WeNMR project has implemented numerous web-based services to facilitate the use of advanced computational tools by researchers in the field, using the grid computational...
Dr
Li Xue
(Utrecht University)
20/03/2018, 14:30
Biomedicine & Life Sciences Applications
Oral Presentation
Proteins and other biomolecules, such as DNA and RNA, are the minimal functional entities that realize life. Understanding how they execute their functions through their 3D structures and interaction dynamics provides a fundamental view of what defines life. This knowledge also allows us to exploit or modify these elegant molecules for a wide variety of purposes, such as gene therapy, drug...
Prof.
Lee-Wei Yang
(National Tsing Hua University)
20/03/2018, 15:00
Biomedicine & Life Sciences Applications
Oral Presentation
To combat antibiotic resistance demands timely improvement of drug efficacy. Here we introduce a computational approach that systematically creates variants from known antimicrobial peptides (AMPs) and selects the ones with improved potency based on physical quantities computed from a short, so called “immerse and surface” (IAS), molecular dynamics (MD) simulation. The designed in-silico...
