Conveners
Health & Life Science Applications
- Jung-Hsin Lin (Academia Sinica)
Health & Life Science Applications
- Jung-Hsin Lin (Academia Sinica)
Protein-protein recognition through the hydrogen-bonded chains of interfacial water is a less explored mechanism due to the technical challenges involved in the analyses, and the role of waters in forming a stable protein-protein complex is often elusive. It is still unclear whether and how the hydrogen-bonded interfacial-water chains contribute to triggering or participating in the...
The Coherent Multirepresentation Problem (CMP) was recently proposed as a generalization of the well-known and widely studied Distance Geometry Problem (DGP). Given a simple directed graph G, the idea is to associate various types of representations to each arc of the graph, where the source vertices are supposed to play the role of reference for the corresponding destination vertices. Each...
The continuous development of the methods for the protein structure prediction was taking advantage from the precious experimental information obtained by structural biology as well as by sequencing of multiple organisms. Indeed, the general developed pipeline is based on determining conformations of protein fragments, and then using multiple sequence alignments to obtain long-range distances...
Modern technologies for DNA and RNA sequencing allow for fast, parallel reading of multiple DNA lines. While sequencing the first genome took 32 years, today with Next Generation Sequencing technologies we are able to sequence 40 genomes in about 2 days, producing 4 TB of text data (a file of about 100 GB per genome). This ability poses a challenge to computing infrastructures, which need to...
Background & Motivation
3D Ultrasound Computer Tomography (3D USCT) is developed at the
Karlsruhe Institute of Technology for early breast cancer detection.
Unlike conventional ultrasound sonography methods with manual guided
ultrasound (US) probes, the patient is placed on a patient bed with a
stable and reproducible measurement configuration. A reproducible stable
measurement...
During the COVID-19 pandemic, there has been a rapid growth of literature and the need to access useful information quickly to understand its disease mechanisms, define prevention techniques, and propose treatments, therefore text classification has become an essential and challenging activity. LitCovid represents an example of the extent to which a COVID-19 literature database can grow: it...
