15-20 March 2026
BHSS, Academia Sinica
Asia/Taipei timezone

Conformal Prediction for Reliable Uncertainty Quantification in Scientific AI Models

18 Mar 2026, 14:22
22m
Auditorium (3F, BHSS)

Auditorium

3F, BHSS

Oral Presentation Track 10: Artificial Intelligence (AI) Artificial Intelligence (AI) - I

Speaker

Luca Clissa (University of Bologna & INFN)

Description

Reliable uncertainty quantification is essential in scientific applications, where predictive results must be supported by a transparent assessment of confidence. Among the many approaches proposed for this purpose, Conformal Prediction (CP) is especially compelling because it offers finite-sample, distribution-free coverage guarantees and can calibrate uncertainty on top of any trained model without requiring retraining.
Using the Higgs Uncertainty Dataset as a benchmark, we illustrate how CP can produce prediction intervals with guaranteed coverage levels while making no assumptions about the underlying data distribution. We also compare CP with traditional likelihood-based inference and common ML-driven uncertainty estimation techniques to highlight their respective strengths and limitations. Taken together, these results show that CP provides a competitive and flexible approach that integrates seamlessly with existing ML workflows, making it a promising building block for the development of trustworthy and reproducible AI in scientific research.

Primary authors

Daniele Bonacorsi (University of Bologna) Dr Leonardo Plini (University La Sapienza) Luca Clissa (University of Bologna & INFN)

Presentation materials

There are no materials yet.