Conveners
Biomedicine & Life Science I
- Jung-Hsin Lin (Academia Sinica)
Prof.
Alexandre Bonvin
(Utrecht University)
3/9/17, 2:00 PM
Biomedicine & Life Sciences Applications
Structure determination of complex molecular machines requires combination of an increasing number of experimental methods with highly specialized software geared towards each data source to properly handle the gathered data. Recently we introduced the two software packages PowerFit [1,2] and DisVis [3]. These combine high-resolution structures of atomic subunits with density maps from...
Dr
Ion I. Moraru
(UCONN Health)
3/9/17, 2:30 PM
Biomedicine & Life Sciences Applications
NMRbox is a shared computational platform for NMR which aims to simplify and integrate the dissemination, maintenance, support, and application of NMR data processing and analysis software packages. From the NMRbox perspective, the collection of myriad tools has enabled (1) development of meta-packages that utilize multiple tools to accomplish complex tasks that are beyond the scope of...
Dr
Tsyr-Yan Yu
(Inst. of Atomic & Molecular Sciences, Academia Sinica)
3/9/17, 3:00 PM
Biomedicine & Life Sciences Applications
Oral Presentation
To harness the resolving power of high-field NMR spectroscopy, non-uniform sampling (NUS) methods and efficient data reconstruction methods are absolutely required to obtain NMR spectra at otherwise unreachable spectral resolution in indirect dimensions. I will describe necessity of NUS methods in high-field NMR spectroscopy and my experience using the methods developed by Wagner laboratory at...
Prof.
Jose Maria Carazo Garcia
(National Center for Biotechnology - CNB - CSIC)
3/9/17, 3:20 PM
Biomedicine & Life Sciences Applications
Oral Presentation
Modern electron microscopes equipped with direct electron detectors are nowadays providing 2D images (“micrographs”) with quasi atomic resolution. However, the way from 2D image collection to the calculation of accurate structural maps showing the electrostatic potential of biological macromolecules demands complex image processing operations, involving many local optimizers. Naturally, the...
